TY - BOOK AU - Royston,Patrick AU - Sauerbrei,Willi TI - Multivariable model-building : : a pragmatic approach to regression analysis based on fractional polynomials for modelling continuous variables / SN - 9780470028421 PY - 2008/// CY - Hoboken, NJ : PB - John Wiley, KW - Anàlisi de regressió KW - lemac KW - Polinomis KW - ANÁLISIS DE REGRESIÓN KW - REGRESSION ANALYSIS KW - ANÁLISIS MULTIVARIABLE KW - MULTIVARIATE ANALYSIS KW - MODELOS ESTADÍSTICOS KW - STATISTICAL MODELS KW - MÉTODOS DE INVESTIGACIÓN KW - RESEARCH METHODS KW - MANUAL KW - HANDBOOK N1 - Inclou referències bibliogràfiques i índex. N2 - Multivariable regression models are of fundamental importance in all areas of science in which empirical data must be analyzed. This book proposes a systematic approach to building such models based on standard principles of statistical modeling. The main emphasis is on the fractional polynomial method for modeling the influence of continuous variables in a multivariable context, a topic for which there is no standard approach. Existing options range from very simple step functions to highly complex adaptive methods such as multivariate splines with many knots and penalisation. This new approach, developed in part by the authors over the last decade, is a compromise which promotes interpretable, comprehensible and transportable models ER -